A Microphysiological Model of Metastatic Progression

Using systems to model metastatic progression

In this webinar, we discuss how to use systems to model metastatic progression, evaluate therapeutics and improve our understanding of the bidirectional crosstalk that occurs between host tissue cells and the metastatic cancer cells.

Speaker Information:
Dr Amanda Clark

Research Assistant Professor
University of Pittsburgh

Watch this webinar to learn:

  • How to model dormant-emergent metastatic progression
  • The impact of scaffolding materials on the metastatic niche and therapeutic efficacy
  • The impact of Organ-on-a-Chip technologies on our understanding of:
    - bidirectional crosstalk between parenchymal cells
    - metastatic tumor cells 

Metastatic disease is the leading cause of mortality in patients with solid tumors. Despite decades of research, we only partially understand the underlying cellular and molecular mechanisms.

This gap in knowledge represents a significant barrier for the prevention and treatment of metastasis. In part, a lack of relevant accessible model systems capable of capturing the complexities of metastatic disease progression has hindered our progress. As a result, researchers are turning towards tissue engineered ex vivo biomimetic microphysiological systems.

Other webinars from our Autumn & Summer series

Join industry leaders in a series of webinars focused on Organ-On-Chip technology

The scars of fat

The transability of 3D NASH microtissues to model human/murine NASH

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The Rhythm of Life

Using Microfluidics To Mimic Blood Flow in Single- and Multi-Organ-on-a-Chip . . .

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A regulators viewpoint

Establishing strategies to evaluate microphysiological systems for drug . . .

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